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avatar for John Malone

John Malone

Assistant Professor of Genetics and Genomics in the Department of Molecular and Cell Biology and Institute of Systems Genomics at the University of Connecticut
John Malone is Assistant Professor of Genetics and Genomics in the Department of Molecular and Cell Biology and Institute of Systems Genomics at the University of Connecticut. His laboratory uses genetic, genomic, bioinformatic, evolutionary, and statistical approaches to explore how gene copy number influences gene expression and evolution. A major project underway is the generation of genome assemblies for amphibians to understand the evolution of sex chromosomes in vertebrates. This work involves collaboration with researchers in Latin America, Africa, and Japan to conduct fieldwork and to collect samples in order to answer what regions of vertebrate genomes contribute to sex chromosomes and how this genomic diversity relates to the function of animal genomes as sex chromosomes evolve. A second project is the study of polyploid animals to understand how genome doubling influences gene function and physiological systems. John is a member of the Global Young Academy (GYA) an international organization of 200 outstanding early stage career scientists seeking to give voice to early-staged career researchers and to contribute to solving global problems using science.